Study Evaluating Serum Collected From Healthy Adults For Development of Pneumococcal Opsonophagocytic Assay

Blood Collection In Healthy Adult Volunteers To Obtain Serum For Use In Pneumococcal Opsonophagocytic Assay Development.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00508950

Enrollment

152

Registered

2007-07-30

Start date

2007-08-31

Completion date

2016-06-30

Last updated

2016-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Vaccines, Pneumococcal Conjugate Vaccine, Adult

Brief summary

The study will identify healthy adults who have been vaccinated against pneumococcus, and collect blood for the purpose of developing laboratory assays.

Detailed description

Collect serum with antibody levels capable of killing pneumococcal bacteria from healthy prevaccinated adults to develop OPA assays for the 13 serotypes in 13-valent pneumococcal conjugate vaccine.

Interventions

PROCEDURELarge volume blood draw

Large volume blood draw

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy adults 18-70 years of age * Must have received 23vPS pneumococcal vaccine

Exclusion criteria

* Bleeding diathesis * Pregnancy * Chronic disease which could be worsened by donating blood * Receipt of blood, blood products or immune globulin within six months

Design outcomes

Primary

Measure	Time frame
To identify potential serum donors and obtain unit volumes of blood from these donors for use in pneumococcal opsonophagocytic assay development.	8 years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026