Functional Outcomes Following Limb Sparing Surgery for Sarcoma Patients

Functional Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma and Pre-Operative Radiotherapy

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00508339

Enrollment

Registered

2007-07-27

Start date

2006-09-30

Completion date

2007-10-31

Last updated

2012-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcoma

Keywords

Soft Tissue Sarcoma, Limb Sparing Surgery, Toronto Extremity Salvage Score, Radiotherapy, Quality of Life, Questionnaire, Survey, TESS

Brief summary

Primary Objectives: 1. To classify the types of wound healing complications that occur after pre-operative radiation therapy and limb sparing resection for the treatment of soft tissue sarcomas of the extremity. 2. To evaluate the impact of each complication type on patient function and quality of life using the Toronto Extremity Salvage Score (TESS).

Interventions

BEHAVIORALQuestionnaire

Toronto Extremity Salvage Score (TESS) questionnaire.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Diagnosis of soft tissue sarcoma with histopathologic confirmation. 2. Treatment protocol that includes pre-operative radiation therapy. 3. Treatment protocol that includes limb-sparing surgical resection. 4. Patient has received MD Anderson Cancer Center multidisciplinary care. 5. Patient must be at least three years post-operative.

Exclusion criteria

1. Previous radiotherapy to the local site. 2. Presence of regional or distant metastases. 3. Major medical co-morbidities (eg. cerebrovascular accident, congestive heart failure, concurrent malignancy) or disabilities unrelated to treatment for soft tissue sarcoma.

Design outcomes

Primary

Measure	Time frame
Endpoints for this study will be anatomic site, histological subtype, primary wound closure, wound complication type, need for secondary operation and type of secondary operation.	1 Year

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026