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Cognitive and Emotional Impairment After Stroke

Cognitive and Emotional Impairment After Stroke

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00506818
Enrollment
250
Registered
2007-07-25
Start date
2007-02-28
Completion date
2009-06-30
Last updated
2009-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Impairment, Stroke, Vascular Dementia

Keywords

emotional symptoms, vascular risk-factors

Brief summary

Cognitive and emotional symptoms are often seen in the acute phase of a stroke. The prevalence of such symptoms later and the mechanisms explaining the symptoms are not fully known. The causes of poststroke dementia are likely to be multifactorial (Cerebrovascular Diseases 2006). The investigators want to include all patients with first ever stroke without significant cognitive decline prior to the stroke (IQCODE cut-off 3,7) and follow them up for one year. At baseline we will make stroke classifications, measure neurological deficits according to NIHSS, evaluate cognitive and emotional function and make registrations of vascular risk factors, including precerebral color duplex scan with measurement of IMT in CCA. The investigators will then randomize the patients into multifactorial vascular-risk-factor-intervention in the hospital or care as usual in the primary health care. 8-12 months after stroke onset, survivors will undergo new examinations to evaluate neurological, cognitive and emotional functions, as well as MRI and SPECT.

Interventions

OTHERMultifactorial vascular-risk-factor-intervention

Sponsors

University of Oslo
CollaboratorOTHER
Sykehuset Asker og Baerum
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE

Eligibility

Sex/Gender
ALL

Inclusion criteria

* First ever stroke or TIA * No cognitive decline (IQCODE \< 3,7) * Survived the acute stroke * Expected to live at least for one year after stroke

Exclusion criteria

* Cognitive decline

Design outcomes

Primary

MeasureTime frame
Effects of vascular risk-factor-intervention on changes in TMTA, ten-words-test and HAD8-12 months after stroke onset

Secondary

MeasureTime frame
Prevalence of dementia and depression after stroke8-12 month after stroke onset

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 9, 2026