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Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00502398
Enrollment
Unknown
Registered
2007-07-17
Start date
2007-09-30
Completion date
Unknown
Last updated
2007-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Artery Hypertension

Brief summary

Patients with hemolytic disorders (e.g. sickle cell anemia or thalassemia) are known to develop pulmonary hypertension. Hemolysis is where red blood cells are destroyed and their contents released into the circulation. It is thought that these red-cell contents cause constriction and thrombosis of the blood vessels in the lungs. Conversely, it is possible that patients with pulmonary hypertension have hemolysis. In this study we will be drawing blood from a range of patients and normal controls for a panel of blood tests related to hemolysis.

Interventions

PROCEDUREBlood test

Sponsors

Rabin Medical Center
Lead SponsorOTHER

Study design

Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

One of the following four conditions : * Pulmonary artery hypertension * Obstructive sleep apnea with pulmonary hypertension * Lung transplant candidates without pulmonary hypertension * Normal Controls

Exclusion criteria

* Known hemolytic disorder * Recent blood loss (\<3 months) * Recent blood transfusion (\<3 months) * Liver disease

Countries

Israel

Contacts

Primary ContactBen Fox, MRCP
foxb@clalit.org.il+972 3 937 7221

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026