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Anisometropia Amblyopia Improved by Perceptual Learning and Patching

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00498641
Enrollment
Unknown
Registered
2007-07-10
Start date
2005-01-31
Completion date
2007-01-31
Last updated
2007-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anisometropic Amblypia

Keywords

perceptual learning, occlusion therapy

Brief summary

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Detailed description

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

Interventions

PROCEDUREcomputer program and patching

Sponsors

Tri-Service General Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE

Eligibility

Sex/Gender
ALL
Age
3 Years to 55 Years
Healthy volunteers
Yes

Inclusion criteria

* Anisometropia without strabismus * An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization * All patients wore their spectacle at least one year

Exclusion criteria

* A history of prior spectacle correction * A history of patching or optical penalization * The existence of an ocular disease that could contribute to decreased visual acuity * Learning difficulties * The presence of strabismus

Design outcomes

Primary

MeasureTime frame
Corrected amblyopic logMAR visual acuity and contrast sensitivity function

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026