Melatonin and Adiponectin in Hypertensive Kidney Transplant

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00498576

Enrollment

Registered

2007-07-10

Start date

2007-09-30

Completion date

Unknown

Last updated

2009-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Kidney Transplant

Keywords

hypertension, kidney transplant, melatonin, adiponectin

Brief summary

Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients. The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus normal hypertensive patients. Secondly, to ask if there is any correlation between melatonin secretion and adiponectin levels.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* hypertension * kidney transplantation ( group 1) * good renal function

Exclusion criteria

* diabetes mellitus * cancer * renal failure

Countries

Israel

Outcome results