Anemia, Iron-Deficiency
Conditions
Keywords
Anemia, Iron-Deficiency, Endoscopy, Gastrointestinal, Male, aged 18 to 40
Brief summary
Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia. Due to lack of data on the yield of these endoscopies in young men, they are currently investigated as older men. The aim of this study is to evaluate prospectively the prevalence of various gastrointestinal lesions in young men with iron deficiency anemia. Our hypothesis is that the diagnostic yield of colonoscopy in young anemic men without gastrointestinal symptoms is very low, especially if a potential lesion is detected during upper gastrointestinal endoscopy. Therefore, this study will try to identify predicting factors regarding the yield of both endoscopies. Another purpose is to evaluate the outcome of patients with negative endoscopic results, during a follow-up of two years.
Interventions
PROCEDUREupper gastrointestinal endoscopy, colonoscopy
Sponsors
Assaf-Harofeh Medical Center
Study design
Observational model
DEFINED_POPULATION
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Men \< 40 years old of age with iron deficiency. * hemoglobin level less than 13 gr/dl documented during the 2 years prior to entering the study with one of the following: 1) iron level less than 45 μg /dl and transferrin saturation less than 10%; 2) ferritin level less than 20 μg/L (both documented during the 4 months prior to entering the study).
Exclusion criteria
* Previously diagnosed disease that explain iron deficiency anemia * Colonoscopy performed during the last 4 years * Upper gastrointestinal endoscopy performed during the last 2 years
Countries
Israel
Contacts
Primary ContactAlain Nimrod Kimchi, M.D.
Backup ContactEfrat Broide, M.D.
Outcome results
None listed