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Health Related QOL, Depression and Lifestyle Changes in Insulin Resistant Adolescents

Health-related Quality of Life, Depression and the Impact on Successful Incorporation of Lifestyle Changes in Insulin Resistant Adolescents as Evidenced by Changes in BMI, Waist Circumference and Metabolic Parameters

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00493259
Enrollment
78
Registered
2007-06-28
Start date
2007-06-30
Completion date
2008-06-30
Last updated
2021-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Insulin Resistance

Keywords

Health-Related Quality of Life

Brief summary

The purpose of this study is to assess adolescents with Insulin Resistance Syndrome for quality of life and altered health related issues.

Detailed description

Matched historical control study designed to examine outcomes on insulin resistant adolescents who were treated in the Insulin Resistance Syndrome Clinic at Children's Mercy Hospital in the past year. New patients will be screened at baseline, 4 and 12 months to evaluate if there is improvement in the BMI Z-score, HgA1c, lipid profile or waist circumference when depression and/or altered health related quality of life are identified and treated in this population.

Interventions

BEHAVIORALHealth-Related Quality of Life instrument

Adolescents will fill out questionnaires regarding quality of life and dealing with diagnosis of Insulin Resistance Syndrome

BEHAVIORALDepression Scale for Children (CES-DC)

questionnaire

Sponsors

Children's Mercy Hospital Kansas City
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
11 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* Patients 11-17 years of age who are seen in the Insulin Resistance Clinic for the first time * Historical control: Patients 11-19 years of age seen in the Insulin Resistance Clinic during the prior four months

Exclusion criteria

* Co-morbid syndrome (Downs, Turner's, Prader Willi etc) * Diagnosis of Type 2 Diabetes * Taking Metformin before the initial visit * Taking medication for or diagnosis of a psychiatric condition prior to initial visit * Developmentally delayed

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026