Corneal Opacity, Keratitis
Conditions
Keywords
PTK, corneal opacity, mitomycin
Brief summary
The present study was designed to evaluate the treatment of adenoviral corneal opacities with PTK and mitomycin C.
Detailed description
Epidemic keratoconjunctivitis is a very common disease, some patients developed a complication after the infection wich is corneal infiltration. Topical treatment sometimes helps to avoid loss of visual acuity. Therefore recurrence of the opacities after topical drops is observed. When corneal fibrosis occur is difficult to achieve visual rehabilitation with topical approach. This study evaluate pre and postoperative data of patients with subepithelial fibrosis caused by adenoviral infiltrates submitted to phototherapeutic keratectomy (PTK) using mitomycin C.
Interventions
PROCEDUREPTK with mitomycin in Adenoviral Opacities
Sponsors
Federal University of São Paulo
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* visual acuity worse than 20/40, caused by central subepithelial fibrosis
Exclusion criteria
* pregnancy, age less than 18 years-old or more than 80 years-old. * diabetes, autoimmune diseases, corneal thickness less tha 400 micron.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Refractive data, visual acuity, slit lamp findings, subjective evaluation, topography patterns, pachymetry measurements. | one year |
Secondary
| Measure | Time frame |
|---|---|
| wavefront analysis, anterior segment tomography data, corneal biomechanics data. | one year |
Countries
Brazil
Outcome results
None listed