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Comparison of CL Wear Between Two Allergy Drops

Comparison of CL Wear Between Epinastine Hydrochloride and Olopatadine Hydrochloride

Status
Withdrawn
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00489398
Enrollment
25
Registered
2007-06-21
Start date
2007-07-31
Completion date
2008-12-31
Last updated
2010-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Conjunctivitis

Brief summary

Comparison of two allergy drops for enhancing comfort and performance of contact lens wear

Detailed description

Contact lens patients will instill allergy drops and subjective and objective tests will be performed

Interventions

DRUGepinastine HCL and olopatadine HCL

Sponsors

Merck Sharp & Dohme LLC
CollaboratorINDUSTRY
Hom, Milton M., OD, FAAO
Lead SponsorINDIV

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Males or females \> 18 years old * Mild to moderate dry eye symptoms * Likely to complete all study visits and able to provide informed consent

Exclusion criteria

* Current use of topical cyclosporine * Known contraindications to any study medication or ingredients * Active ocular diseases or uncontrolled systemic disease (blepharitis patients that are actively being treated or disease that is uncontrollable) * Ocular surgery within the past 3 months

Design outcomes

Primary

MeasureTime frame
Contact lens objective and subjective clinical performance testingup to 3 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026