Distal Ureterolithiasis
Conditions
Brief summary
We will performe a prospective randomized study to evaluate the effects of the addition of alfuzocine xl 10 mg once a day for the conservative treatment of selected ureteral stones. A total of 60 patients with distal ureteral calculi will randomly divide into two treatment groups: group A (n=30) who will receive only analgetic therapy(Dipyrone)and diclofenac i.m. 75mg and group B (n=30) who will receive the same therapy plus alfuzocin xl (10 mg/daily) for a maximum of 2 weeks.No significant differences will be between the groups for age, gender distribution and mean stone size measured in the single largest dimension at presentation.Randomization will be done only with the patients permission after they had read a summary describing the goals of conservative management and a description of the drugs they would be taking. Potential side effects and complications of the drugs were discussed. The expulsion rate will the primary end-point of this study.
Interventions
DRUGAlfuzocine XL 10 mg once a day
Sponsors
HaEmek Medical Center, Israel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* Stone in the distal ureter until 1 cm of diameter
Exclusion criteria
* Evidence of urinary tract infection or sepsis * Moderate or severe hydronephrosis * Acute renal failure * Ureteral stricture * Stone with \>1cm of diameter * Previuos use of alpha blocker * Pregnancy * Previuos ureteral endoscopic or open surgery
Countries
Israel
Contacts
Primary ContactDORON PEREZ, M.D.
Outcome results
None listed