Cesarean Section
Conditions
Keywords
Regional anesthesia, Fluid Therapy, Hemostasis, Surgical
Brief summary
Cesarean section-associated hypotension is one of the pivotal factors to influence the Apgar Score of children and related with the stable hemostasis during the whole process of labor. How to keep circulation in a consistent stability is yet to be known. The investigators hypothesized that different fluids, crystalloids or colloids, can produced varying effects in keeping the physiological environment of labor from significant fluctuating.
Interventions
OTHERRinger's Lactate
Ringer's Lactate was used 15min before operation
OTHER6% Starch
6% Starch was used 15min before operation
Sponsors
HRSA/Maternal and Child Health Bureau
Nanjing Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
21 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* 21-40 yr * First time of delivery * ASA status I-II * No premature * No genetic and infectious diseases * Chinese
Exclusion criteria
* \< 21 yr * \> 40 yr * Subjects with cardiac and pulmonary disorders * Dislocation of placenta * Pregnant hypertension * Allergy to local anesthetics * Unwilling to cooperation * Need intraoperative administration of vascular active agents * With significant delivery side effects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total volume of colloid Total volume of crystalloid Total fluid volume | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Percentage reduction in hematocrit, Days in hospital | 6 months |
Countries
China
Outcome results
None listed