Acquired Heart Disease, Atherosclerosis, Congenital Heart Disease, Myocardial Infarction, Myocardial Ischemia
Conditions
Keywords
Transthoracic echocardiography, Ischemia, Cardiovascular Disease
Brief summary
This study will evaluate volunteers 18 years of age and older to see if they qualify for one of NHLBI s research studies. Tests include the following: * General medical evaluation, which may include blood tests, chest x-ray, electrocardiogram (ECG) and echocardiogram (heart ultrasound). * Other tests as appropriate, such as magnetic resonance imaging (MRI), cardiac computed tomography (CT scan of the heart), nuclear stress test and echocardiography stress test. * X-ray contrast studies of the heart and blood vessels. (These may be excluded in patients with kidney risk factors.)
Detailed description
This is a screening protocol. This protocol allows two functions: 1) the protocol allows physicians in the Suburban/NHLBI Cardiovascular Imaging program to evaluate patients referred to the program with clinically indicated studies and research studies. 2) It is also designed to determine if patients may be suitable candidates for one of our NHLBI research protocols. Patients greater than or equal to 18 years of age referred for possible cardiovascular disease will be enrolled in the protocol for a period of one year. At one year, patients will either be: 1) transferred to one of our specific research MRI or CT protocols, 2) removed from the screening protocol and made inactive, or 3) re-enrolled on the screening protocol with the patient s consent.
Interventions
DEVICEToshiba Aquilion ONE CT
The Toshiba Aquilion ONE CT system has the ability to acquire whole organ volume images in a single rotation by utilizing an x-ray detector that is configured as 320 detector rows with a 0.5 mm width, providing a z-axis coverage of 16 cm of anatomy.
DEVICESWiemens MRI scanner
Investigational or research MRI coils may be used in the protocol. The coils are noninvasive devices external to the body. The coils act as antennae to receive small radiofrequency signals out of the body. Coils of the type we use are used daily in clinical MRI practice.
Sponsors
National Heart, Lung, and Blood Institute (NHLBI)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ELIGIBILITY CRITERIA: No one will be excluded from this study based on race, gender, or ethnicity. A. General Inclusion Criteria: * Age greater than or equal to 18 * Capable of giving informed consent. B. General
Exclusion criteria
* Pregnant women (uncertain patients will have urine or blood testing). * Decompensated heart failure (unable to lie flat in bed). Test Specific
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complete characterization of patients for screening purpose onto a research protocol. | Ongoing | Complete characterization of patients for the purpose of deciding whether they are eligible for research protocols run by the Cardiovascular Branch. |
Countries
United States
Outcome results
None listed