Asthma
Conditions
Brief summary
A study to test the effect of MK0359 in lessening the symptoms of asthma as compared to placebo.
Interventions
DRUGMK0359
Sponsors
Merck Sharp & Dohme LLC
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* You are between the ages of 18 and 45 * You have had a history for at least a year of COPD symptoms * Your current asthma treatment is limited to short-acting beta-agonists(such as albuterol) * You have a history of smoking one pack of cigarettes per day for 7 years * You will not be away from home for more than 5 days during the study
Exclusion criteria
* You are unwilling to limit your alcohol use to less than 5 drinks per week * You have been in a research study with an investigational drug or vaccine in the last 4 weeks * You have donated blood in the last 4 weeks * You have been hospitalized or had major surgery in the last 4 weeks * You have been treated in the emergency room within the last 4 weeks or hospitalized within the last 3 months for your asthma * You have a history of heart problems in the last 6 months * You have a history of stomach problems * You are unwilling to avoid grapefruit juice throughout the study
Outcome results
None listed