Obesity
Conditions
Brief summary
To assess the effect of MK0493 on body weight, blood pressure, mood, and appetite.
Interventions
DRUGMK0493
Sponsors
Merck Sharp & Dohme LLC
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patient is between 21 and 65 years * Patient is able to read and understand and complete study questionnaires * Patient is not pregnant or breast-feeding and does not plan to become pregnant for the duration of the study and post-study follow-up period
Exclusion criteria
* Patient has a history of significant psychiatric disorder (such as major depression, bipolar disorder, bulimia, or anorexia nervosa * Patient is HIV positive as determined by medical history * Patient has undergone surgical treatment for obesity * Patient plans to consume more than two 8 ounce glasses of grapefruit juice per day during the study * Patient participated in another clinical study involving an investigational drug) within 3 months prior to Visit 1 * Patient is currently a heavy consumer of alcohol (\>2 drinks per day or \>14 drinks per week \[1 drink is defined as 2 oz hard alcohol, 5 oz wine, 12 oz beer\], or uses (including recreational use) any illicit drugs, or has a history of drug or alcohol abuse
Outcome results
None listed