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Systematic Pelvic Lymphadenectomy Versus no Lymphadenectomy in Clinical Stage I-II Endometrial Cancer

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00482300
Enrollment
Unknown
Registered
2007-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2007-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial Cancer

Keywords

Histologically proved endometrial carcinoma preoperatively supposed stage I-II

Brief summary

The purpose of this trial is to determine whether the addition of systematic pelvic lymphadenectomy to hysterectomy with bilateral adnexectomy improves disease-free survival (DFS) and overall survival (OS) in patients with preoperatively supposed Stage I-II endometrial cancer

Interventions

PROCEDURESystematic pelvic lymphadenectomy

Sponsors

University of Roma La Sapienza
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
No minimum to 75 Years
Healthy volunteers
No

Inclusion criteria

* Histologically proven endometrioid or adenosquamous endometrial carcinoma. * Patients having myometrial invasion * Age =/\< 75 years * Informed consent.

Exclusion criteria

* Serous papillary and clear cell tumors. * Karnofsky index \< 80 or severe diseases contraindicating surgery * Concomitant neoplasia (basalioma cutis excluded) * Distant metastasis or abdominal metastasis detected intraoperatively. * Absence of myometrial invasion at frozen section.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026