The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00481585

Enrollment

Registered

2007-06-01

Start date

2007-05-31

Completion date

Unknown

Last updated

2014-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

claudin, electrophysiology, breast, screening

Brief summary

The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3. Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC.

Exclusion criteria

* From within this population, no

Design outcomes

Primary

Measure	Time frame
Cell line data study	one year

Countries

United States

Outcome results