Non-Invasive Determination of Cardiac Output by Inertgas Rebreathing Method

Non-Invasive Determination of Cardiac Output by the Inertgas Rebreathing Method Compared With Magnetic Resonance Tomography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00479804

Acronym

NICO

Enrollment

311

Registered

2007-05-28

Start date

2006-08-31

Completion date

2007-12-31

Last updated

2008-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Diseases

Keywords

indication for CMR

Brief summary

The cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The current standard methods for the determination of the CO, however, are either invasive (e.g. right heart catheterization) or technically expendable and expensive (magnetic resonance tomography, MRT). The traditional non-invasive methods of determining the CO by rebreathing of carbon dioxide are easily carried out but suffer from methodical inaccuracies. Therefore the aim of the study at hand was to evaluate a new method for determining the CO by means of the inert gas rebreathing method.

Interventions

DEVICEinertgas rebreathing

determination of cardiac output by inertgas rebreathing

DEVICEspirometry

spirometry for testing the ventilatory function

DEVICEcardiac magnetic resonance imaging (CMR)

CMR examination which delivers the hemodynamic reference parameters

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

14 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Indication for CMR * Ability of following instructions for rebreathing test

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026