Analysis of Human Tear Proteins in Children

Analysis of Human Tear Proteins in Children: A Pilot Study to Describe the Tear Film Proteome of Pediatric Patients Undergoing Ophthalmic Examination.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00473278

Enrollment

Registered

2007-05-15

Start date

2007-01-31

Completion date

2009-06-30

Last updated

2013-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Disease

Keywords

tear protein

Brief summary

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film, and any unique aspects of tears in children. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 17 Years

Healthy volunteers

Yes

Inclusion criteria

* Less than 18 years of age * A parent or legal guardian provide written informed consent to participate * Able to cooperate with tear sample collection, or a previously planned sedation for other medical purposes

Exclusion criteria

* Age greater than or equal to 18 years * Patients' parents or legal guardians who refuse to sign study consent

Design outcomes

Primary

Measure	Time frame
Proteome of Human Tears	Single Exam

Countries

United States

Outcome results