Trial of Excision Versus Photodynamic Therapy in the Treatment of Bowen's Disease

A Randomized Clinical Trial of Excision Versus Photodynamic Therapy in Bowen's Disease

Status

Terminated

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00472706

Enrollment

Registered

2007-05-14

Start date

2007-05-31

Completion date

2010-02-28

Last updated

2010-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowen's Disease

Keywords

Treatment, Excision, Photodynamic therapy, Recurrence rate, Cosmetic outcome

Brief summary

The purpose of this study is to identify the most optimal therapy for Bowen's disease: excision versus Photodynamic therapy.

Detailed description

The study is a randomized clinical trial in which two treatment options for Bowen's disease, excision and photodynamic therapy, are compared on recurrence rate, cosmesis en expenses.

Interventions

PROCEDUREexcision

excision 3 mm margin

PROCEDUREPhotodynamic therapy

Photodynamic therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Histological proven Bowen's disease on scalp, face, trunk, arms and legs * Informed Consent

Exclusion criteria

* Recurrent Bowen's disease * Anogenital or subungual Bowe's disease * Other skin malignancy in the same area * Porphyria

Design outcomes

Primary

Measure	Time frame
recurrence rate	two years

Secondary

Measure	Time frame
cosmetic outcome	one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026