Pancreaticojejunostomy After Pancreatic Head Resection
Conditions
Brief summary
Previously we have demonstrated in animal experiments,that pancreas is extremely vulnerable to handling, reacting with the development of pancreatitis. In human pancreatic surgery, post-operative pancreatitis mediates many other post-operative complications. A new anastomosis was developed to diminish the injury, as being without any stitches going through the pancreas. The aims were to study up to 30 patients as phase one study, with an interim analysis in this open uncontrolled trial after the first few patients.
Interventions
PROCEDUREPancreaticojejunostomy without stiches through the pancreas
The pancreas is cut with knife, without electric cautery and without stay sutures. Bleeding is controlled with 2-3 exactly placed stiches. The pancreatic stump is sunk inside the jejunum, which is tightened around the pancreas with a purse string. A biodegradable stent is left into the pancreatic duct to prevent its occlusion when tightning the purse string.
Sponsors
Tampere University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients scheduled to undergo peancreatic head resection
Exclusion criteria
* Those who refuse from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pancreatic fistula, other complications | One year from operation |
Secondary
| Measure | Time frame |
|---|---|
| Patency of the pancreaticojejunostomy | One year |
Countries
Finland
Contacts
Primary ContactIsto H Nordback, M.D.
Outcome results
None listed