Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer

Feasibility Clinical Study: Accuracy of the P2X7 Biomarker in Detection of Endometrial Cancers in Women

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00471120

Enrollment

Registered

2007-05-09

Start date

2006-11-30

Completion date

2008-02-29

Last updated

2015-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial Cancer, Uterine Cancer

Brief summary

This study aims at developing an accurate, simple, and cost-effective method for screening and early detection of uterine cancers

Detailed description

The present study aims at developing an accurate, simple and cost-effective method for screening and early detection of uterine cancers in women using novel inventions and biotechnology methods for collection and assay of uterine cells. Results of P2X7 assays using tissues obtained from women with known uterine cancer and from women with histologically normal endometrium will be compared. These data will also serve as basis for future studies to test the predictive value of the method in population-based studies.

Interventions

OTHERP2x7 assay

compare P2X7 assay to biopsy

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* women scheduled to undergo hysterectomy * ages 18 years and older

Exclusion criteria

* pregnant women * students or employees under the direct supervision on the investigators.

Design outcomes

Primary

Measure	Time frame
To determine the accuracy potential of the P2X7 (protein and mRNA levels) for the detection of uterine endometrial cancers in women.	Upon review of the assays.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026