Refractive Surgery and Optive Compatibility Study

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00469157

Enrollment

Registered

2007-05-04

Start date

2007-05-31

Completion date

2008-04-30

Last updated

2008-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye Syndromes

Keywords

compatibility of Optive after PRK or LASIK

Brief summary

To assess the compatibility of Optive with refractive surgery (PRK and LASIK) post-operatively.

Interventions

DRUGOptive

Optive 30ml- (in the eye) Instill one in each eye twice daily starting one week after surgery

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Men and women 18 and over * Patients undergoing refractive surgery

Exclusion criteria

* Concurrent ocular conditions or pathology that could affect patient's ability to complete study * Concurrent use of topical medications other than study medications * Use of systemic medications with ocular drying sequelae: * Antihistamines * Decongestants * Antispasmotics * Antidepressants

Design outcomes

Primary

Measure	Time frame
Assess compatibility	8 months

Secondary

Measure	Time frame
comfort	8 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026