Short Term Comparative Study of Xalatan With Benzalkonium Chloride vs. Travatan Z Without Benzalkonium Chloride in Healthy Volunteers

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00468988

Enrollment

Registered

2007-05-03

Start date

2007-05-31

Completion date

2007-07-31

Last updated

2012-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Brief summary

Compare the effect of Xalatan with benzalkonium chloride on the ocular surface to those effects observed with Travatan Z without benzalkonium chloride after a single dose

Interventions

DRUGTravatan® Z

DRUGXalatan®

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adults with primary open-angle glaucoma, ocular hypertension or pigment dispersion glaucoma

Exclusion criteria

* Age

Design outcomes

Primary

Measure	Time frame
Tear Break Up Time	Day

Secondary

Measure	Time frame
Safety	Onset

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026