Traditional Versus ScvO2 Guided Perioperative Fluid Therapy

Randomized Clinical Study of Traditional Versus ScvO2 Guided Perioperative Fluid Therapy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00468793

Enrollment

240

Registered

2007-05-03

Start date

2007-04-30

Completion date

2009-05-31

Last updated

2009-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative Care

Keywords

central venous saturation, bowel surgery, morbidity, intravenous infusions

Brief summary

Perioperative goal directed fluid therapy by means of an esophageal doppler has been shown to reduce morbidity and length of stay. In this study patients undergoing elective bowel surgery will be randomised to traditional fluid therapy with crystalloids versus fluid boluses guided by central venous oxygen saturation. The primary outcome will be complications after surgery.

Interventions

PROCEDUREIntravenous fluid

The same intravenous fluids will be used in both arms but the volume will be different

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Elective bowel surgery, * Able to give informed consent

Exclusion criteria

* Coagulation defect, * Renal failure, * Valvular stenosis

Design outcomes

Primary

Measure	Time frame
Postoperative morbidity	postoperative day 30

Secondary

Measure	Time frame
serum creatinine	postoperative day 3

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026