Melasma
Conditions
Brief summary
The objective of this study is to evaluate laser treatment and acid peel for the treatment of melasma.
Detailed description
The purpose of this study is to evaluate the safety and efficacy of laser treatment and acid peel for the treatment of melasma.
Interventions
PROCEDURELaser Treatment
Laser treatment to half of the face at each study visit
PROCEDUREAcid Peel
Acid peel to half of the face at each study visit
Sponsors
Northwestern University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of melasma lesion measuring at least 4 square centimeters. * Age 18-75 years. * Good health. * Willingness and ability to understand and provide informed consent for participation in the study. * Ability to communicate with the investigator. * Must be willing to forgo other treatment options for melasma during the course of the study.
Exclusion criteria
* Inability to understand the protocol or to give informed consent. * Mental illness. * Under 18 years of age and over 75 years of age. * Laser treatment in the last 6 months before enrollment. * Isotretinoin within the past year. * Lidocaine allergy. * History of herpes simplex viral infection. * Concurrent active disease to facial area (i.e acne). * Bleeding disorder. * History of abnormal wound healing. * History of abnormal scarring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MASI | 20 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Safety | 20 weeks |
Countries
United States
Outcome results
None listed