Effect of Dietary Salt Supplemantation in Vasovagal Syncope Prophylaxis: A Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00465946

Enrollment

Registered

2007-04-27

Start date

2004-06-30

Completion date

2007-06-30

Last updated

2007-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Salt supplementation, Vasovagal syncope, Orthostatic tolerance, Healthy volunteers

Brief summary

Syncope is a syndrome consisting of a relatively short period of temporary and self-limited loss of consciousness caused by transient diminution of blood flow to the brain (most often the result of systemic hypotension). The objective of this study was to evaluate the effect of salt supplementation in vasovagal syncope prophylaxis.

Detailed description

Healthy volunteers without use of medicines with except contraceptives orals that met the exclusion criteria were consecutively enrolled in a randomized trial.

Interventions

BEHAVIORALSalt Supplementation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers

Exclusion criteria

* Use medicines * Previous diseases * Incapacity of to understand and to sign the term consent

Design outcomes

Primary

Measure	Time frame
Evaluate the effectiveness of the salt supplementation in the prophylaxis of the vasovagal syncope	—

Secondary

Measure	Time frame
Evaluate the supplementation salt increases the orthostatic tolerance	—
Analyze the supplementation salt increases the plasmatic volume	—

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026