Continuous Glucose Monitoring (POC) in the ICU

Continuous Glucose Monitors (CGM) Versus Point-of-Care (POC) Glucometers in the Intensive Care Unit (ICU)

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00464386

Acronym

POC

Enrollment

Registered

2007-04-23

Start date

2006-09-30

Completion date

2013-12-31

Last updated

2016-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns, Trauma

Keywords

Severe burns, Severe Trauma, Closed loop insulin, continuous glucose monitoring

Brief summary

The purpose of this study is to prospectively evaluate whether the addition of continuous glucose monitoring to point-of-care (POC) glucometer monitoring improves glucose control.

Detailed description

Severe burns and traumatic injury can be associated with protracted illness and prolonged ICU course. The beneficial effects of strict serum glucose control in critically ill surgical patients have been demonstrated. Continuous glucose monitors may improve glucose control by providing close to real-time glucose measurements, giving the critical care team the ability to react to trends before hypo- or hyperglycemia is reached. These improvements may decrease the morbidity and mortality associated with severe thermal injury, thereby minimizing hospital stay and recovery. Burned and injured soldiers, airmen, sailors, and marines may return to duty in a more expeditious fashion, or at minimum, enjoy a better quality of life after discharge from the intensive care unit.

Interventions

DEVICEContinuous Glucose Monitoring

measure glucose levels on burn patients

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 72 Years

Healthy volunteers

Inclusion criteria

* remain 1 week in an ICU * 18-72 years old * severe trauma or thermal injury greater than 20% TBSA burn

Exclusion criteria

* cerebral arterial injury * myocardial infarction * pre-existing renal failure or liver failure * history of hypoglycemia * history or high risk of seizures * pregnancy

Design outcomes

Primary

Measure	Time frame
To prospectively evaluate the reliability of continuous glucose monitors and the advisability of their use in patients with severe trauma and or thermal injury.	90 days

Secondary

Measure	Time frame
To investigate whether the use of continuous glucose monitoring systems in the ICU results in better glucose control.	90 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026