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The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00463502
Enrollment
Unknown
Registered
2007-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2007-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus, Type 2

Keywords

The purpose of study was investigated the effect of, metformin on thyroid hormone metabolism in euthyroid patients, with type 2 DM. The results revealed significant decreases, in TSH and fT4

Brief summary

Aim: To investigate the effects of metformin treatment on thyroid hormone metabolism in euthyroid patients with type 2 diabetes mellitus.

Interventions

DRUGMetformin

Sponsors

Haydarpasa Numune State Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
35 Years to 78 Years

Inclusion criteria

* The patients included in this study were the ones who were newly diagnosed with type 2 diabetes mellitus

Exclusion criteria

* Presence of thyroid disorders, positive thyroid autoantibodies and usage of medications affecting thyroid hormones such as amiodarone, lithium were accepted as exclusion criterions

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026