Healthy
Conditions
Keywords
Diet, elderly, age-related diseases, prevention, cognitive decline, Clinical study
Brief summary
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
Detailed description
The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects. Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.
Interventions
BEHAVIORALdiet
Sponsors
University Hospital Muenster
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy subjects * 50-80 years old * moderate to heavy weight * must be able to change diet at home
Exclusion criteria
* diabetes * younger than 50 years * BMI \< 23 * already participating in other studys * MMSE \> 26 * eating disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| implicit visual-motor learning of a finger sequence of the hand. | — |
Secondary
| Measure | Time frame |
|---|---|
| implicit learning of an artificial language | — |
| several plasma levels related to cognitive functions | — |
Countries
Germany
Outcome results
None listed