Cluster Headache
Conditions
Keywords
Comparison of a spontaneous acute cluster headache attack and rest (no pain) in ten patients with cluster headache defined with IHS criteria
Brief summary
Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache 'Sprenger et al, 2004). This prompted the application of hypothalamic deep brain stimulation. The aim of this data is to precise the localisation of the hypothalamic activation.
Interventions
PROCEDUREposition emission transaxial tomography
cerebral position emission transaxial tomography using 18Fluorodeoxyglucose
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* cluster headache in crisis * no serious illnesses in progress as cancer, autoimmune disease, liver disease * patient without chronic psychiatric disease excluding moderate and reactional depression * no demential disease * no anxious or depressive disease * no contraindication to PET scan (pregnancy and breast-feeding) * social security cover * written informed consent
Exclusion criteria
* No effective contraception taken * unable to realize a decubitus of 15 minutes long
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To confirm the existence of a hypothalamic promoter at the origin of Spontaneous Cluster Headache Attacks | 2 years |
Countries
France
Outcome results
None listed