Pregnancy
Conditions
Keywords
Amniotic fluid, D-dimer, coagulation, factor X activation
Brief summary
Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.
Detailed description
Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.
Interventions
None listed
Sponsors
Rambam Health Care Campus
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Women undergoing amniocentesis during 15-35 weeks of gestation.
Exclusion criteria
* A history of venous thromboembolism * Systemic disease i.e.; diabetes, hypertension, hypo or hyper-thyroidism, * Anticoagulant treatment * Abnormal embryo
Countries
Israel
Contacts
Primary ContactGalit Sarig, Ph.D
Outcome results
None listed