Endocrine and Nutritional Assessment in B Thalassemia Major

Endocrine and Nutritional Assessment in B Thalassemia Major - A Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00456690

Enrollment

133

Registered

2007-04-05

Start date

2007-05-31

Completion date

2014-12-31

Last updated

2019-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thalassemia

Keywords

Thalassemia, Nutrition, Endocrine, BMI

Brief summary

B Thalassemia patients developed short stature and low weight in spite no evident endocrine abnormalities. One hypothesis is that they developed some degree of malnutrition,then the purpose of this study is to assess the nutritional status before nutritional intervention and after one year. Siblings of the patients will serve as a control group. BMI, lipid and endocrine profile and leptin levels will be analysed in the study group only.

Detailed description

The nutritionist will advice the patients about calories requirement and intake, balance diet and follow up the patients during the study period of one year. No special medicaments or drug therapy will be provided as part of the study protocol

Interventions

OTHERNutritional recommendations

Nutritional status assessment including complete endocrine and lipid laboratory profile and after one year of nutritional follow up a secondary assessment will be done

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

5 Years to 40 Years

Healthy volunteers

Inclusion criteria

* All patients above age 5 ys treated in the clinic.

Design outcomes

Primary

Measure	Time frame
BMI	1 year study

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026