Invasive Infections in Children With Hemoglobinopathies

Invasive Infections in Children With Hemoglobinopathies. A Clinical Descriptive Retrospective Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00456443

Enrollment

200

Registered

2007-04-05

Start date

2006-01-31

Completion date

2006-06-30

Last updated

2007-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sickle Cell Anemia, Thalassemia

Keywords

Thalassemia, Sickle cell anemia, Splenectomy, Infections, Streptococcal Pneumonia

Brief summary

Patients diagnosed as having hemoglobinopathies are exposed to serious bacterial infections, principally those patients that underwent splenectomy. Since the introduction of anti pneumococcal vaccine the incidence decreased significantly but other bacteria besides encapsulated bacteria takes place as principal cause of invasive infections. The purpose of this study is to analyse in a retrospective study the incidence of those infections in a group of patients suffering from thalassemia and sickle cell anemia treated in our clinic.

Interventions

PROCEDUREHistorical records

Study design

Observational model

DEFINED_POPULATION

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

No minimum to 40 Years

Healthy volunteers

Inclusion criteria

* All patients treated in the Pediatric Hematology Unit.

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026