Pilot Study of Human Tear Proteins

Analysis of Human Tear Proteins: A Pilot Study to Describe the Tear Film Proteome of Patients Undergoing Ophthalmic Examination.

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00453258

Enrollment

Registered

2007-03-28

Start date

2007-02-28

Completion date

2011-09-30

Last updated

2013-01-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Disease

Keywords

ocular proteomics, eye disease, proteomics

Brief summary

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film from diseased and non-diseased patients. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Interventions

OTHEREye Examination

Subjects receiving eye examination

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* 18 years of age and older * able to cooperate with tear sample collection * provide written informed consent

Exclusion criteria

* special populations (children, pregnant or lactating females, prisoners, etc) * refusal to sign sudy consent

Design outcomes

Primary

Measure	Time frame	Description
Plan Prospective Research	Throughout study participation	Pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026