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Cortisol in the Treatment of Phobias

The Efficacy of Cortisol in Combination With Behavioral Therapy in the Treatment of Phobias

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00451750
Enrollment
40
Registered
2007-03-23
Start date
2007-05-31
Completion date
2009-09-30
Last updated
2010-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Phobia

Keywords

phobia, cortisol, memory, treatment

Brief summary

The aim of this prospective, double-blind, placebo-controlled, randomized study is to investigate if glucocorticoid treatment, in combination with exposure therapy, helps to reduce phobic fear in patients with phobia.

Interventions

DRUGCortisol

20 mg for 3 times

Sponsors

University Hospital, Basel, Switzerland
CollaboratorOTHER
University of Zurich
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

\- Female and male patients with a specific phobia (fear of heights) according to DSM-IV criteria.

Exclusion criteria

* Severe acute or chronic somatic diseases * Psychiatric disorder other than specific phobia * Topic glucocorticoid therapy (for large skin parts) * Inhaled glucocorticoids * Psychotropic medication * Pregnancy

Design outcomes

Primary

MeasureTime frame
visual analog scales for fear and acrophobia questionnaires1 month

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026