FindTrial
Sign In

Metabolic Effects of Cocaine

Elucidating the Role of the Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Mechanisms Underlying Cocaine Dependence

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00451230
Enrollment
15
Registered
2007-03-23
Start date
2005-06-30
Completion date
2005-06-30
Last updated
2017-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine Dependence

Keywords

craving, insulin, leptin

Brief summary

The goal of this this study is to elucidate the role of the HPA axis in the pathophysiology of cocaine dependence

Interventions

DRUGcocaine
DRUGhydrocortisone

Sponsors

National Alliance for Research on Schizophrenia and Depression
CollaboratorOTHER
National Institute on Drug Abuse (NIDA)
Lead SponsorNIH

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Masking
DOUBLE

Eligibility

Sex/Gender
ALL
Age
21 Years to 49 Years
Healthy volunteers
No

Inclusion criteria

* Individuals with DSM IV diagnosis of cocaine dependence, medically healthy

Exclusion criteria

* Other than cocaine dependence DSM-IV axis I diagnosis

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026