Macular Pigment Optical Density
Conditions
Keywords
visual caracteristics, macular pigment optical density, visual acuity, contrast sensibility, lutein, docosahexaenoic acid (DHA)
Brief summary
The purpose of this study is to determine the benefits of Visiobiane Anti-age dietary supplement on macular pigment optical density, contrast sensibility and visual acuity. Additionally, the study would like to evaluate seric variations of carotenoids and the total antioxydant capacity.
Detailed description
Visiobiane study is a randomized trial of 30 participants designed to assess the effects of oral supplementation of macular xanthophylls (lutein and zeaxanthin) and omega-3 LCPUFAs for the eyes protection. The study will enroll healthy participants aged 45 to 55 years. 15 subjects will be assigned in placebo group and 15 in experimetal group (Visiobiane anti-age). They will be supplemented for 24 weeks
Sponsors
PiLeJe
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE
Eligibility
Sex/Gender
MALE
Age
45 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy caucasian men * age : 45-55 * BMI \< 25
Exclusion criteria
* non healthy * retinian and/or visual anomaly * Ocular media not clear enough to allow good fundus photography
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| macular pigment optical density | — |
Secondary
| Measure | Time frame |
|---|---|
| contrast sensibility | — |
| visual acuity | — |
| seric carotenoids concentrations | — |
| total antioxidant capacity | — |
| influence of SR-B1 genetic polimorphism | — |
Countries
France
Outcome results
None listed