Effect of Repeated Exposures to Compressed Air on Patients With AIDS

Effect of Repeated Exposure to Compressed Air on Patients With AIDS (Acquired Immunodeficiency Syndrome)

Status

Withdrawn

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00444847

Acronym

DANET1

Enrollment

Registered

2007-03-08

Start date

2005-07-31

Completion date

Unknown

Last updated

2017-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS

Keywords

AIDS, HIV, Hyperbaric Chamber, treatment experienced

Brief summary

The exposure of human beings to markedly altered environments (ambient pressure and inhaled gas mixtures) has profound effects on their innate immune capacity to effectively combat viral illnesses. This Phase IIA clinical trial examines the effects of an exposure to a 4 atmospheric environment has on HIV-infected humans whose clinical condition has progressed to formal AIDS status.

Interventions

DEVICEHyperbaric chamber

Study design

Allocation

NON_RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* CD4 count \<200 * Viral load \> 5000

Exclusion criteria

* Opportunistic infection * Concurrent neoplasm (see protocol) * Immunomodulators * HIV vaccination * Investigational HIV drugs (see protocol) * Pregnant women * Major organ transplant

Design outcomes

Primary

Measure	Time frame
1 - Safety	—
2 - Viral Load measure (blood and intracellular)	—
3 - CD4/CD8 levels	—

Secondary

Measure	Time frame
ADL measurements	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026