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Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study

Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance in Children With Scintigraphically Prooved Obstruction. A Prospective, Randomized, Controlled Multi-Center Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00444431
Acronym
TOKU
Enrollment
240
Registered
2007-03-07
Start date
2007-03-31
Completion date
Unknown
Last updated
2007-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral Ureteropelvic Junction Obstruction

Brief summary

In this randomized trial surgical therapy and surveillance of ureteropelvic junction obstruction will be compared, regarding partial renal function.

Interventions

PROCEDUREPyeloplasty

Sponsors

University Hospital, Essen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
4 Months to 6 Months
Healthy volunteers
No

Inclusion criteria

* unilateral ureteropelvic junction obstruction * diameter of renal pelvis greater 12 mm * partial renal function of 35%-55% proofed by scintigraphy * urodynamically relevant decrease in renal drainage proofed by diuresis scintigraphy at the age of 4 weeks up to 6 months * Abscence of clinical symptoms * Healthy contralateral kidney

Exclusion criteria

* Global decrease in renal function * renal dystopia * megaureter * vesico-ureteral reflux * progressive hydronephrosis * oligohydrammnion * voiding dysfunction * bilateral hydronephrosis * severe chronical illness * decrease of partial renal function of more then 5% during allocation

Design outcomes

Primary

MeasureTime frame
partial renal function—

Countries

Germany

Contacts

Primary ContactAchim Rose, Md
roseachim@web.de00492017233221

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026