Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00442091

Enrollment

Registered

2007-03-01

Start date

2010-12-31

Completion date

2019-12-31

Last updated

2020-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pompholyx, Vesicular Palmoplantar Eczema

Keywords

Dandelion, herbal remedy, hand eczema, Compositae

Brief summary

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

Detailed description

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients. The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Interventions

DRUGdandelion juice

10 ml bid for 20-30 days

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

Exclusion criteria

* Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months. * Pregnancy, lactation. * Compositae contact allergy. * Liver or gall bladder disease. * Abnormal renal or hepatic blood tests.

Design outcomes

Primary

Measure	Time frame
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.	3-4 weeks

Secondary

Measure	Time frame
Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).	3-4 weeks

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026