Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00441753

Enrollment

Registered

2007-03-01

Start date

2006-09-30

Completion date

Unknown

Last updated

2009-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest, Post-Anoxic Encephalopathy

Brief summary

Survivors of a cardiac arrest frequently develop severe postanoxic encephalopathy. Derangements in cerebral blood after return of spontaneous circulation play an important role in the pathogenesis of postanoxic encephalopathy. In the present study we examine the effect of mild therapeutic hypothermia on cerebral blood flow and carbondioxide reactivity in patients after cardiac arrest.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 95 Years

Healthy volunteers

Inclusion criteria

* adult patients * GCS after return of circulation \< 7 * Induced mild hypothermia for 24 hours * primary rhythm ventricular fibrillation

Exclusion criteria

* Thrombolysis * Cardiogenic shock with expected survival \< 24 hrs * Pregnancy * No informed consent

Countries

Netherlands

Contacts

Primary ContactCornelia Hoedemaekers, MD PhD

C.Hoedemaekers@ic.umcn.nl00.31.24.3617273

Outcome results