Lung Cancer
Conditions
Keywords
alfentanil, anesthesia, bronchoscopy, lidocaine, midazolam, propofol.
Brief summary
The objective of the study was to establish which anesthetic procedure used during flexible bronchoscopy has the lowest index of complications.
Detailed description
This prospective randomized study analyzed 80 patients that underwent flexible bronchoscopy. Patients were randomly assigned to four groups of 20 patients each according to the anesthetic combination used: 200 mg topical lidocaine (LID group); 200 mg topical lidocaine and 2 mg/kg propofol (PPF group); 200 mg topical lidocaine and 20 mcg/kg alfentanil (ALF group); or 200 mg topical lidocaine and 0.05 mg/kg midazolam (MID group). Scores were assigned to patients according to the different variables observed during the endoscopic procedure; the lower the score, the lower the complication index.
Interventions
DRUGpropofol
DRUGmidazolam
DRUGalfentanil
DRUGlidocaine
Sponsors
Hospital Pompeia
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* The patients included in this study were referred to FBC for the investigation of bronchial carcinoma (diagnostic procedure). * Patients included in the study were classified as ASA I, II and II according to the anesthetic risk classification of the American Society of Anesthesiologists (ASA).
Exclusion criteria
* ASA IV classification of anesthesiology risk * procedure that lasted longer than 15 minutes * indication of therapeutic bronchoscopy * cardiac arrhythmia and / or hypoxemia detected at admission.
Countries
Brazil
Outcome results
None listed