Brain Tumor, Cancer
Conditions
Keywords
cancer, electromagnetic fields, treatment
Brief summary
In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. We have identified specific frequencies that may block cancer cell growth. We have developed a device delivering low levels of amplitude-modulated electromagnetic fields. The device is connected to a spoon-like coupler, which is placed in the patient's mouth during treatment. We will conduct a feasibility study consisting of three daily ambulatory treatments until disease progression.
Detailed description
Background: In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. We have identified specific frequencies that may block cancer cell growth. We have developed a portable and programmable device delivering low levels of amplitude-modulated electromagnetic fields. The device is connected to a spoon-like coupler, which is placed in the patient's mouth during treatment. Methods: We will conducted a feasibility study consisting of three daily treatments. All patients with advanced solid tumors and measurable disease will be eligible, irrespective of prior treatments. Patients will be assessed with laboratory exams (complete blood count, comprehensive profile, tumor markers), imaging studies every other month for the first six months, every third month thereafter.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Advanced tumor that is either metastatic or inoperable
Exclusion criteria
* Pregnancy, * Other simultaneous anticancer therapies, * ECOG performance status less than 3
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of daily administration of amplitude-modulated electromagnetic fields in patients with advanced cancer | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete blood count, comprehensive chemistry profile, tumor markers | — |
| Tumor assessment as per RECIST criteria | — |
Countries
Switzerland