Glucose in Dialysis Water in Diabetics With Chronic Renal Failure

Effect of Glucose in Dialysis Water in Diabetics With Chronic Renal Failure on Blood Pressure, Pulse Rate, Plasma Glucose, Plasma Concentrations of Insulin, Growth Hormone, Renin, Angiotensin II, Endothelin and Body Temperature

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00438503

Enrollment

Registered

2007-02-22

Start date

2006-05-31

Completion date

2007-05-31

Last updated

2015-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Failure, Chronic, Diabetic Nephropathies

Keywords

Hemodialysis, diabetes mellitus,, Chronic renal failure, dialysis ,

Brief summary

The purposes are 1. to measure the effect of dialysis with glucose in dialysis water on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and 2. to analyse the relationship between the changes in blood pressure and changes in vasoactive hormones

Detailed description

The relationship between blood pressure during dialysis treatment and vasoactive hormones are studied. This includes measurements of plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin

Interventions

PROCEDUREProcedure

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age \> 18 years, 2. Both men and women, 3. Dialysis treatment for at least three month due to diabetic nephropathy

Exclusion criteria

1. Heart failure, 2. Lung insufficiency, 3. Chronic liver disease, 4. Malignant disease, 5. Nephrotic syndrome, 6. Lack of compliance, 7. Unwillingness to participate

Design outcomes

Primary

Measure	Time frame
Effect og glucose in dialysis water on blood pressure, plasma glucose and hormones in plasma	—

Secondary

Measure	Time frame
Relationship between changes in blood pressure and and changes in hormones	—

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026