Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea

Status

Suspended

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00438412

Enrollment

Registered

2007-02-22

Start date

2006-10-31

Completion date

Unknown

Last updated

2008-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Keywords

Noradrenalin, Endothelin-1, Angiotensin II, Arginine vasopressin, Aldosterone, Renin, Atrial natriuretic peptide, Brain natriuretic peptide, Blood pressure, Apnea

Brief summary

The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones during apneic events during sleep.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Patients with Obstructive sleep apnea Inclusion Criteria: * Severe obstructive sleep apnea (apnea-hypopnea index \> 30)

Exclusion criteria

* Drug or alcohol abuse * Pregnancy * History or clinical signs of disease in the heart, lungs, brain, liver, kidneys or endocrine organs * Diabetes Healthy Controls Inclusion Criteria: * Apnea-hypopnea index \< 10

Countries

Denmark

Outcome results