Antabuse in Severe Alcoholism: an Open Controlled Study

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00431262

Enrollment

Registered

2007-02-05

Start date

2007-02-28

Completion date

2009-06-30

Last updated

2007-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcoholism

Keywords

alcoholism, antabuse, disulfiram, abstinence, cognitive behavioural therapy

Brief summary

Newly detoxified alcoholics (N=60) are randomised to either antabuse (disulfiram) treatment or the control group for a total of 6 months.All patients will receive cognitive behavioural treatment in groups. The hypothesis to be tested is that more of the patients who receive antabuse (disulfiram) will be alcohol free during the 6 months treatment period compared to the control group. The trial is open.

Interventions

DRUGantabuse (disulfiram)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Alcoholism * Living in the departments catchment area

Exclusion criteria

* Pregnancy * Schizophrenia * Bipolar disorder * Other substance abuse * Dementia * Anorexia

Design outcomes

Primary

Measure	Time frame
The number of patients in each group who have not been drinking alcohol after 6 months of treatment.	—

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026