Radiotherapy for Malignant Astrocytomas in the Elderly

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00430911

Enrollment

Unknown

Registered

2007-02-02

Start date

2001-02-28

Completion date

Unknown

Last updated

2007-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaplastic Astrocytoma, Glioblastoma Multiforme, Primary Brain Tumor

Keywords

malignant gliomas

Brief summary

A randomized trial comparing radiotherapy with supportive care in patients aged 70 years or older with newly diagnosed, histologically confirmed anaplastic astrocytoma or glioblastoma, and a Karnofsky performance status \> 70.

Interventions

DRUGRadiotherapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

70 Years to No maximum

Healthy volunteers

Inclusion criteria

* Glioblastoma and anaplastic astrocytoma, supratentorial, histologically confirmed * Brain CT scan or MRI within 28 days before surgery * Age: 70 years or older * Karnofsky performance status, 70 or more. * Life expectancy over 12 weeks * Informed consent

Exclusion criteria

* Brain radiotherapy * Chemotherapy * Severe systemic disease

Design outcomes

Primary

Measure	Time frame
Survival	—

Secondary

Measure	Time frame
Progression free survival	—
Quality of life	—
Cognitive functions	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026