Schizoaffective Disorder, Schizophrenia
Conditions
Keywords
work therapy, cognitive rehabilitation, schizophrenia, schizoaffective disorder, treatment outcome
Brief summary
This research investigates the benefits of productive activity and cognitive rehabilitation for patients with schizophrenia. Key questions are: 1. does cognitive rehabilitation plus work activity produce better outcomes than work activity alone? 2. Is cognitive rehabilitation more helpful for individuals with moderate or greater cognitive impairment than for individuals without such impairment? 3. Does cognitive rehabilitation reduce the dropout rate and increase participation in work activity for cognitively impaired subjects? 4. What features of cognitive rehabilitation are most important for clinical and rehabilitation outcomes?
Detailed description
This is a randomized, matching study in which subjects are stratified by degree of cognitive impairment, then randomly assigned to one of two conditions: Work Services Only vs. Work Services plus cognitive rehabilitation. Longitudinal analysis of work activity, work performance, symptoms, quality of life, cognitive function and service utilization are made.
Interventions
BEHAVIORALcognitive rehabilitation
computer training
PROCEDUREwork therapy
opportunity to work in carefully supervised hospital job
Sponsors
VA Connecticut Healthcare System
VA Office of Research and Development
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* diagnosis of schizophrenia or schizoaffective disorder
Exclusion criteria
* change in psychiatric medications or housing within 30 days of study intake * episode of drug abuse within 30 days of study intake * GAF score 30 or less * known neurological disease or developmental disability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological test performance | data collection completed |
Secondary
| Measure | Time frame |
|---|---|
| Hours of productive activity | data collection completed |
| Hours worked | data collection completed |
| Quality of life | data collection completed |
| Psychiatric symptoms | data collection completed |
Countries
United States
Outcome results
None listed