HIV Infections
Conditions
Keywords
HIV, HAART, Nutrition, Dyslipidemia
Brief summary
Highly active antiretroviral therapy (HAART) in HIV-positive patients is associated with the development of dyslipidemia, a risk factor for cardiovascular events. The objective of this study was to evaluate the effect of dietary intervention in individuals who start HAART.
Detailed description
Adult patients prescribed to HAART that met the exclusion criteria were consecutively enrolled in a randomized trial: * control (receiving general guidelines on dietary education) * intervention (receiving general guidelines on dietary education and nutritional follow-up every 3 months)
Interventions
BEHAVIORALNutritional
Sponsors
Hospital de Clinicas de Porto Alegre
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* HIV-positive individuals naive to HAART, with clinical indication to start therapy
Exclusion criteria
* Diabetes Mellitus * Pregnancy * Active opportunistic disease * Any mental deficiency * Use of lipid profile influencing drugs * Use of illicit drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total cholesterol and of triglycerides levels | — |
Secondary
| Measure | Time frame |
|---|---|
| HDL-cholesterol, LDL-cholesterol, weight, waist to hip ratio | — |
Countries
Brazil
Outcome results
None listed